Hydroxytriazenes- A Promising Class of Anti-Inflammatory Compounds
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چکیده
Hydroxytriazenes behave like bidentate ligands which have alpha hydroxyl group relative to azo group. The synthesis includes reduction of an alkyl or aryl nitro compound in neutral medium to get hydroxylamine and diazotization of an aromatic amine to get diazonium chloride. When these two that is hydroxylamine and respective diazonium salt are coupled we get hydroxytriazene as a product. A general scheme reported by Elkins and Hunter and further modified by Sogani & Bhattacharya [11] for synthesis of hydroxytriazenes is as shown in Scheme 1.
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